Supramamillary Nucleus


A transient supramamillary nucleus was apparent at 14 w.g.  

A transient supramamillary nucleus was apparent at 14 w.g.  

However in the ventrolateral medulla (A1/C1 catecholamine neurons), nucleus of the solitary tract (A2/C2 catecholamine neurons), lateral parabrachial nucleus, supramamillary nucleus, bed nucleus of the stria terminalis, accumbens core and medial prefrontal cortex no differences in the withdrawal treatments were detected.  

Few well-defined nuclei exhibited positive TLR4 transcript: the supramamillary nucleus, cochlear nucleus, and the lateral reticular nucleus.  

Our results demonstrate that there was a direct relationship between a significant increase in c-fos labelling and the amount of PS in the laterodorsalis tegmenti in the pons, supramamillary nucleus, septum, hippocampus, gyrus cingulate, amygdala, stria terminalis and the accumbens nuclei.  

The first group included nuclei showing clustered, intensely labeled cells; these areas were restricted in extent and related to the maintenance of circadian rythms (intergeniculate leaf, suprachiasmatic nucleus, dorsal parts of either paraventricular thalamic nuclei or central gray), sleep-arousal cycle (supramamillary nucleus), or changes in arterial pressure (laterodorsal tegmental nucleus).  

In our study, dense networks of melanin concentrating-hormone-immunoreactive varicose fibers were observed in the supramamillary nucleus, the lateral hypothalamus, the nucleus medialis thalami and nucleus reuniens and in the bed nucleus of the stria terminalis..  

The supramamillary nucleus showed moderately dense fiber networks, while the dorsal premamillary and the posterior hypothalamic nuclei were poor in peptidergic fibers..  

PTHrP gene expression was highest in the supramamillary nucleus of the hypothalamus, medial superior olivary nucleus, and in subpopulations of cells in the neostriatum, hippocampus, and cerebral cortex.  

Several other areas appeared to project only to the region immediately dorsal to the SON: lateral septal nucleus, diagonal band of Broca, ventral tegmental nucleus, and the supramamillary nucleus.  

AADC-IR perikarya were also found in the other hypothalamic areas where few or no TH-IR cells have been reported: the supramamillary nucleus, tuberomamillary nucleus, pre- and anterior mamillary nuclei, caudal arcuate nucleus, dorsal hypothalamic area immediately ventral to the mamillothalamic tract, anterior hypothalamic area, area of the tuber cinereum, retrochiasmatic area, preoptic area, suprachiasmatic and dorsal chiasmatic nuclei.  

In the equine species, alpha 2-group cell bodies occupy a shorter anterioposterior field extending from the posterior level of the paraventricular nucleus to the supramamillary nucleus.  

Immunohistochemical studies clearly showed that the perikarya of immunoreactive neurons are most prevalent in the ventral part of the lateral septal nucleus, periventricular preoptic nucleus, bed nucleus of the stria terminalis, periventricular and dorsal parts of the paraventricular hypothalamic nucleus, ventromedial nucleus, dorsomedial nucleus, arcuate nucleus, median mamillary nucleus, supramamillary nucleus, zona incerta, medial habenular nucleus and the periaqueductal grey matter.  

In the hypothalamus, projections came from the periventricular, lateral and posterior part, as well as the supramamillary nucleus.  

The supramamillary nucleus has both oligosynaptic (to neocerebellar cortex) and polysynaptic (to vermal cortex) connections..  

Labeled cells were found in the medial septal area, the diagonal band of Broca, anterior and laterodorsal thalamic nuclei, reuniens and periventricular thalamic nuclei, lateral hypothalamus, supramamillary nucleus, and the dorsal and superior central midbrain raphe nuclei.  

Catecholaminergic perikarya were observed within periventricular, dorsal, and caudal hypothalamic areas as well as within the supramamillary nucleus and caudal diencephalon.  


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